Dipyridamole induces interferon in man.

AS Galabov, M Mastikova - Biomedicine & Pharmacotherapy …, 1984 - europepmc.org
AS Galabov, M Mastikova
Biomedicine & Pharmacotherapy= Biomedecine & Pharmacotherapie, 1984europepmc.org
Thirty-six out of 40 healthy volunteers responded with a markedly elevated blood interferon
(IFN) content to a single oral administration of dipyridamole (a 100 mg dose): 958.0+/-23.5
IU/ml serum at the 24th-48th hour. A hyporeactivity state to the repeated inducer application
was found within the time interval of 4th-6th day. It was established that 7/8 of the
dipyridamole-induced IFN represented IFN-alpha.
Thirty-six out of 40 healthy volunteers responded with a markedly elevated blood interferon (IFN) content to a single oral administration of dipyridamole (a 100 mg dose): 958.0+/-23.5 IU/ml serum at the 24th-48th hour. A hyporeactivity state to the repeated inducer application was found within the time interval of 4th-6th day. It was established that 7/8 of the dipyridamole-induced IFN represented IFN-alpha.
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